Tuesday 31 March 2009

Bio information on HHS nominee Kathleen Sebelius

Bio information on HHS nominee Kathleen Sebelius

NAME — Kathleen Sebelius.

AGE-BIRTH DATE-LOCATION: 60; May 15, 1948; Cincinnati.

EDUCATION — Bachelor's degree, Trinity College, Washington, 1970; master of public administration, University of Kansas, 1978.

CAREER — Kansas governor, 2003-present; insurance commissioner, 1995-2003; Kansas House, 1987-94; executive director, Kansas Trial Lawyers Association, 1978-86; special assistant, Kansas secretary of corrections, 1975-78.

FAMILY — Husband, Gary; two sons, Ned and John.

Monday 30 March 2009

Israeli Biotechs Rally on M&A, State Aid; Bio Light Surges 332%

By Tal Barak Harif and Alisa Odenheimer


March 30 (Bloomberg) -- Israeli biotechnology shares avoided this quarter's slump in global stocks after Johnson & Johnson's buyout of a medical-equipment maker ignited takeover speculation and the government pledged money for research.


Clal Biotechnology Industries Ltd., Israel's second-largest biotech company, doubled and Bio Light Israeli Life Sciences Investments Ltd. surged 332 percent after J&J's buyout of Omrix Biopharmaceuticals Inc. Medical Compression Systems (DBN) Ltd. jumped 80 percent this month as it sold a stake to investment firm Accelmed.


"Investors are speculating which companies will be bought next," said Noa Weisberg, an analyst at Israel Brokerage & Investments Ltd. in Tel Aviv. The credit crunch makes it more likely the firms will agree to be bought as they struggle to borrow, she said.


The 92 percent average gain by Israeli biotech stocks this year outstripped the 15 percent rally in emerging-market information technology shares and trounced the 11 percent slump in the MSCI World Index. Most of the stocks still trade below their initial public offering prices and are valued at less than half of their global competitors relative to cash, according to data compiled by Bloomberg.


Herzliya-based Accelmed wants to invest $2 million to $4 million for stakes of at least 33 percent in companies, Chairman Uri Geiger said in a telephone interview. The investment firm, formed this year to target medical-device makers, will invest 8 million shekels ($1.9 million) for a 26.1 percent stake in Medical Compression Systems, which developed a device to help blood circulation, the Or-Akiva-based company said March 26.


Johnson & Johnson


"These are companies in which you can identify opportunities," said Geiger.


Israel's biotechnology industry gained investors' attention in 2007 when the Tel Aviv Stock Exchange made it easier for research and development firms to sell shares by lowering requirements for capital, minimum investments and the number of shareholders. Fourteen biotechnology companies raised almost 1 billion shekels in share sales that year.


Speculation about acquisitions was fueled after New Brunswick, New Jersey-based Johnson & Johnson, the world's largest maker of healthcare products, agreed on Nov. 24 to pay $438 million, or $25 a share, for Omrix, a New York-based developer of equipment to stem bleeding that has most of its research and manufacturing in Israel. The stock traded at $16.52 on Nov. 20, two trading days before the deal was announced, and at $10 at the IPO in 2006.


Copaxone Treatment


Biotech shares are also rising because the government pledged last month to add about 350 million shekels to the budget of the Office of the Chief Scientist, which funds research programs by technology firms. Israel set up a separate 250 million-shekel biotechnology fund in February to support start-ups through clinical trials and to encourage private investment.


The plan is part of government efforts to tackle what Israel predicts will be the worst recession since its creation in 1948. The central bank forecasts the economy will shrink by 1.5 percent this year.


Israel has patented more medical devices than any other nation per capita, according to the Israel Life Science Industry organization and the U.S. Patent and Trademark Office. Achievements include the Weizmann Institute's Copaxone treatment for multiple sclerosis, bought by Petah Tikva-based Teva Pharmaceutical Industries Ltd. in the 1990s, and Given Imaging Ltd.'s capsule-sized camera for diagnosing digestive ailments in 2001.


Rebound


Gains for biotechnology stocks are surpassed in Israel only by Petah Tikva-based Isramco Negev 2, which surged 787 percent this year after its joint discovery of what may be enough natural gas to supply half the country's energy needs for the next 20 years. Four of the 37 biotechnology stocks listed on the Tel Aviv Stock Exchange fell this year.


The rally may not last, said Steven Tepper, an analyst at Ramat Gan, Israel-based brokerage Prisma Capital Markets Ltd. "Some of what we've seen this year is a rebound as these companies dropped a lot last year," he said.


Even after doubling in the first quarter, Clal Biotechnology is down more than 60 percent from its first day of trading in June 2007, according to Bloomberg data. Israel's 10 biggest biotechnology shares trade at an average 6.8 times their cash, compared with a price-to-cash ratio of 14 for 38 biotechnology stocks worldwide monitored by Bloomberg.


'Legitimacy'


Clal Biotechnology, controlled by Nochi Dankner, who also owns Israel's largest supermarket chain, biggest mobile phone provider and largest insurer, rallied 105 percent this year after receiving approval from the European Medicines Agency for the third phase of its trial to treat skin transplants.


Shares of the Tel Aviv-based company peaked Feb. 18 when Teva, the world's largest generic drugmaker, said it will exercise options to buy $10 million of shares in the Clal's diabetes treatment unit. The shares have declined by 14 percent since then.


"The fact that a company like Teva invests in some of these biomedical companies gives them a certain legitimacy," said Idan Azulay, managing director of Epsilon Mutual Funds in Tel Aviv, which manages $386 million and owns shares of Clal Biotechnology and Jerusalem-based BioCancell Therapeutic Inc. Biocancell has climbed 222 percent this year after receiving U.S. approval to conduct tests to treat ovarian cancer.


Bio Light, which helps treat obesity, glaucoma and cancer, jumped 212 percent on Jan. 7 when the Ramat Gan-based company announced a breakthrough in identifying cervical cancer and pre- cancerous cells. Bio Light shares were last at 0.52 shekel, less than a third of the price when the stock began trading in 2005.


Merger Offers


Brainsway Ltd., Israel's third-largest publicly traded biotechnology company, jumped 213 percent from a low in November. The Jerusalem-based maker of medical devices to treat brain disorders reached an agreement with New Jersey-based Yorkville Advisors LLC in December to provide $15 million over three years. The stock last traded at 6.63 shekels, more than twice its 2007 IPO price.


XTL Biopharmaceuticals Ltd., a developer of neuropathic pain treatments, said in January that it's evaluating "several" merger offers. The stock jumped 41 percent on March 19 after announcing it will buy the rights to use a patent that will prolong life for patients with blood cancer. The shares were last at 0.06 shekel, a fraction of the price of 3.61 on its first day of trading in 2005.


"We can groom these companies until we get out of the global crisis," said Geiger. "If they don't have much debt, they can be seen as good investment opportunities."


To contact the reporter on this story: Tal Barak Harif in Tel Aviv at tbarak@bloomberg.net To contact the reporter on this story: Alisa Odenheimer in Jerusalem at aodenheimer@bloomberg.net.


Stem cells concern biotech leader

Arizona's scientists and citizens are missing out on a potential lucrative source of research funds and medical benefits because of the state's strict limits on embryonic stem-cell research, a top biotechnology official said.


James Greenwood, president of the Washington, D.C.-based Biotechnology Industry Organization, said that Arizona and other states that limit such research methods may not realize the benefits from President Barack Obama's move earlier this month to reverse a ban on federal funding of the controversial research.


"That seems to be a no-brainer," Greenwood said Friday of allowing research of stem cells that are harvested from embryos discarded by fertility clinics. "They are going to be destroyed one way or another."


Arizona's restrictions on embryonic stem-cell research come from two laws passed by the state Legislature. One prevents scientists from conducting research on cells collected from an aborted fetus. Another state law prohibits any public or government research institute from using federal, state or private money on "human cloning," which is defined in a way that blocks the scientific process involved with embryonic stem-cell research, according to the Arizona Attorney General's Office.


Arizona's ban does not apply to other types of stem-cell research, including projects involving adult stem cells or stem cells harvested from a newborn's cord blood. In fact, several Arizona scientists have pursued stem-cell research projects not involving embryonic stem cells.


Arizona's biotech interests largely have not pushed for a change in law to allow embryonic stem-cell research. Some believe the technology may make the ethical issue surrounding such research moot as new methods are developed.


"My hope and expectation is the science will allow research beyond the use of embryonic stem cells, and it will get the same results," said Bob Eaton, president and chief executive officer of the Arizona Bioindustry Association.


Overall, the biotech industry faces more pressing challenges, said Greenwood, who was in Phoenix last week to meet with biotechnology interests. Many companies are fighting for survival because of the recession and investors' aversion to the high-risk, high-reward industry.


A BIO survey released in January showed 30 percent of publicly traded biotech companies reported less than six months of cash on hand, and nearly half all public bio companies had less than a year's worth of cash.


Biotech companies that found a friendly market as recently as two years ago also are noticing the change. Just one of 20 companies that planned an initial public offering last year followed through with the stock offering. Phoenix-based Insys Therapeutics was among the companies that delayed an IPO because of the unfavorable market conditions.


Greenwood, a former U.S. representative from Pennsylvania for 12 years before being named BIO's top executive in January 2005, said his organization is pushing several congressional initiatives to aid the ailing industry.


BIO favors patent legislation that would protect a company's intellectual property for a period of up to 14 years. It can take a biotech firm a decade or longer to develop and market a new drug. Legislation now in Congress would cut down patents to as few as three years, giving biotechnology companies and their investors little incentive to pursue costly research and development, Greenwood said.


The industry group also favors health-care reform that provides universal access, incorporates market-based approaches and promotes innovation, including new drugs and tests.


If lawmakers adopt a plan that hastens the approval and use of generic drugs, it would result in substantial savings for consumers. But Greenwood said it would effectively eliminate the biotechnology industry's incentive to invest in research and development of new drugs, diagnostics and medical devices. Such a move would ultimately gut economic development, resulting in fewer high-paying jobs and less innovation. "We lead the world in this industry," Greenwood said.


But he said significant challenges, including health care and patent reform, threaten to undermine bio firms.


"Investors need to feel comfortable with making large investments," Greenwood said.


BIO-key(R) Granted Patent for Trusted Biometric Device Security Solution

WALL, N.J., March 26, 2009 /PRNewswire-FirstCall via COMTEX/ ----BIO-key International, Inc. (OTC Bulletin Board: BKYI), a leader in finger-based biometric identification and wireless public safety, announced today that the U.S. Patent and Trademark Office has approved the issuance of a patent titled "Trusted Biometric Device," which covers a simple, yet secure method of protecting a user's biometric information.


(Logo: http://www.newscom.com/cgi-bin/prnh/20050509/BIOKEYLOGO)


This patent, (US Patent Number 7,502,938 issued March 10th, 2009) protects the privacy of the user and provides enhanced security for the organization performing the user identity authentication. It covers the transmission of information from the point the information is collected at the biometric reader until the data reaches the computer or device that is authenticating the user's identity. Previous BIO-key patents (including 7,454,624, 7,415,605, and 7,117,356) protect BIO-key's security solutions for transmission of private sensitive authentication data from the client device to a central server authentication point, defending enterprise or centralized authentication applications from security breaches. BIO-key's patents also support the use of standards including the Trusted Computing Platforms, which are embraced by security professionals worldwide.


For the majority of systems today, the biometric data is transmitted "in the clear" with no encryption or protection. As the result, the information is susceptible to malicious attacks from hackers for theft or redirection. Securing the information from the point where it is initially captured (the fingerprint reader) to the computer that is using this information to determine the identity of the user, is a major concern that must be addressed in all applications. This BIO-key solution patent further addresses this need which improves the resulting security of the system, while also offering greater privacy to the user.


"We recognize the need to address not only the privacy of the individual but the security of the total identity transaction. This is the latest in a series of patents granted to BIO-key that secure the biometric template, the communications of the template and the processes handling the identity transaction. It provides another layer of security for our highly accurate, scalable biometric identity solution," stated Mira LaCous VP Technology and Development at BIO-key International.


"With this patent, BIO-key continues to expand our biometric identity solution portfolio. We have the technology to protect the biometric identity transaction from end-to-end. This can be quickly and cost effectively adopted by fingerprint hardware manufacturers as well as commercial application providers that utilize 'remote' authentication. Applications for internet banking, retail and healthcare can easily implement this solution to provide a secure, accurate and convenient method to identify both customers & staff. By deploying this added feature, organizations can instill consumer confidence in the security and accuracy of their solution to attract new and existing customers to their applications that are accessed over the internet," added Mike DePasquale, BIO-key's Chief Executive Officer.


About BIO-key


BIO-key International, Inc., headquartered in Wall, New Jersey, develops and delivers advanced identification solutions and information services to law enforcement departments, public safety agencies, government and private sector customers. BIO-key's mobile wireless technology provides first responders with critical, reliable, real-time data and images from local, state and national databases. BIO-key's high performance, scalable, cost-effective and easy-to-deploy biometric finger identification technology accurately identifies and authenticates users of wireless and enterprise data to improve security, convenience and privacy and to reduce identity theft. Over 1,000 police departments in North America use BIO-key solutions, making BIO-key the leading supplier of mobile and wireless solutions for law enforcement. (http://www.bio-key.com)


Company Contact: BIO-key International, Inc.
Bud Yanak
732-359-1100

SOURCE BIO-key International, Inc.


http://www.bio-key.com

Copyright (C: 2.64, 0, 0%) 2009 PR Newswire. All rights reserved

Books - Thames: The Biography

In this perfect companion to London: The Biography, Peter Ackroyd once again delves into the hidden byways of history, describing the river’s endless allure in a journey overflowing with characters, incidents, and wry observations.


Thames: The Biography meanders gloriously, rather like the river itself. In short, lively chapters Ackroyd writes about connections between the Thames and such historical figures as Julius Caesar and Henry the VIII, and offers memorable portraits of the ordinary men and women who depend upon the river for their livelihoods. He visits all the towns and villages along the river from Oxfordshire to London and describes the magnificent royal residences, as well as the bridges and docks, locks and weirs, found along its 215-mile run. The Thames as a source of artistic inspiration comes brilliantly to life as Ackroyd invokes Chaucer, Shakespeare, Turner, Shelley, and other writers, poets, and painters who have been enchanted by its many moods and colors.


In his signature entertaining and informative manner, Ackroyd allows the reader to dip into chapters in his own spirit, or to follow the Thames from source to sea.
Illustrated with maps and photographs, THAMES is a vivid, highly original mosaic of life by and on the water.


Karo Bio drug cuts cholesterol on top of statins

By Lewis Krauskopf


ORLANDO, Fla., March 29 (Reuters) - Patients taking statin cholesterol-lowering drugs cut their bad LDL cholesterol levels as much 32 percent more when they added an experimental medicine from Karo Bio AB (KARO.ST), according to mid-stage study results released on Sunday.


The drug, eprotirome, also cut triglycerides 15 percent to 33 percent, according to results presented at the American College of Cardiology (ACC) scientific meeting in Orlando. The company had previously said the trial was successful, but did not release specifics.


The results suggest eprotirome has the potential to open a new avenue for treating heart disease, according to a press statement released by the ACC. Eprotirome is designed to target thyroid hormones receptors in the liver that regulate cholesterol.


"This study provides hope for a new add-on treatment of dyslipidemia for patients who are inadequately controlled with, or intolerant to, current lipid-lowering therapy," said Jens Kristensen, Karo's vice president of clinical development.


The 12-week study followed 189 patients who had high cholesterol despite already taking low to moderate doses of two other statins, Merck's (MRK.N) Zocor and Pfizer's (PFE.N) Lipitor. Patients were randomly assigned to one of three doses of eprotirome or a placebo.


Patients on eprotirome cut their LDL cholesterol by 21 percent to 32 percent. Subjects on the placebo cut their LDL 6 percent, as they were likely more compliant with their statin drugs while in the clinical study, according to the company.


There were no observed changes in heart rate or cardiac rhythm and the drug was well-tolerated, the ACC statement said.


Sweden's Karo said the next step will be to confirm the results in a pivotal Phase III study.


Karo said last August the Phase IIb study was successful in lowering LDL and triglycerides, but did not release detailed results at the time. Nonetheless, Karo shares soared on the news.


The company has said it plans to find a partner to help advance eprotirome to the market. (Editing by Maureen Bavdek)


Wednesday 25 March 2009

Presenter Profiles for BIO National Venture Conference 2009

BIO National Venture Conference 2009 takes place March 31 – April 1, 2009 at the Sheraton Boston Hotel in Boston.

Business Wire is the official news wire for BIO National Venture Conference 2009. Breaking news releases, advisories, photos, and multimedia are available at Tradeshownews.com, Business Wire's trade show, conference, and event news resource.

Listed below are the BIO National Venture Conference 2009 presenter profiles.

Company:

Catena Pharmaceuticals, Inc.

Investor Relations Contact: Ian Mehr
Investor Relations Contact Phone: 888-265-1353
Web: www.catenapharma.com
Date of Presentation: April 1, 2009, 2:25 PM
 
While therapeutic advances have been made, cancer remains a scourge as the second leading cause of death in the United States, creating intense suffering and major economic costs on the healthcare system. Catena Pharmaceuticals's proprietary technology has demonstrated a unique ability to aggressively fight the growth of cancerous tumors in animal models. Catena's exciting drug platform attacks cancer through a validated drug target class and by a proven mechanism: blocking blood flow to tumors (angiogenesis) and starving them of oxygen. Catena seeks financing to advance its lead anti-cancer drug candidate, VPC51299, towards human clinical trials.
 
 
Company: GliaMed, Inc.
Investor Relations Contact: Andrew Uprichard, CEO
Investor Relations Contact Phone: 1 (508) 626-0077 x112
Web: www.GliaMed.com
Date of Presentation: 3/31/09
 
GliaMed is developing a small molecule approach to stem cell therapy. Founded in 2001, the company is developing Regenerative Immunophilin Ligands (RILs). In preclinical models, RILs have been shown to induce the localized expression of transcription factors characteristic of pluripotent stem cells at the site of acute disease or trauma. These cells can then be reprogrammed by local signals to become neurons, cardiac myocytes, chondrocytes or other cell types, which then contribute to fully differentiated tissues such as skin. GliaMed's lead candidate, GM1485, has been administered to more than 500 human subjects. The company acquired this compound in 2007.
 
 
Company: Mirna Therapeutics
Investor Relations Contact: Rollie Carlson
Investor Relations Contact Phone: 512-681-5211
Web: http://www.mirnarx.com/
Date of Presentation: 4/1/09
 
Mirna Therapeutics, Inc. ("Mirna") is a biopharmaceutical company focused on miRNA-directed human oncology therapies. Featuring world-class research capabilities, a strong understanding of miRNA and cancer biology, and an expansive IP portfolio, Mirna Therapeutics is well-positioned to be a major "platform" company in the emerging field of miRNA-based therapeutics. Mirna has developed two miRNA drug candidates that are able to inhibit tumor development and metastasis in multiple mouse models of prostate and lung cancer. Mirna is a spin-off of Asuragen, a miRNA-based diagnostics company. Mirna was founded on miRNA technologies and intellectual property first developed at Ambion, Inc. that date back to 2002.
 
 
Company: NeurAxon
Investor Relations Contact: Chris Erdman
Investor Relations Contact Phone: 781-235-3060
Web: www.neuraxon.com
Date of Presentation: April 1, 2009 10:35-10:50am
 
NeurAxon is a leader in discovering and developing next generation pain therapeutics focused on the inhibition of neuronal nitric oxide synthase (nNOS), an enzyme involved in modulating pain and central nervous system neuronal sensitization. NeurAxon has generated a proprietary pipeline of five product candidates for the following indications: acute migraine, neuropathic pain, rheumatoid arthritis, migraine prophylaxis and severe pain. NeurAxon's lead product candidate, NXN-188, is a first-in-class, dual-action small molecule incorporating both nNOS inhibition and 5-HT (5-HT is the mechanism of action of triptans, the largest class of migraine drugs) agonism that is being developed for the treatment of acute migraine.
 

About Business Wire

Business Wire, a Berkshire Hathaway company, is utilized by tens of thousands of member companies and organizations worldwide to functionally enhance and communicate investor relations and public relations content to target audiences. As a recognized disclosure service in the United States, Canada and a dozen European countries, Business Wire facilitates the simultaneous flow of market-moving press releases from corporations to financial markets and their audiences, including regulatory authorities, media, investors, financial information systems and consumer news services. Business Wire also handles XBRL tagging, document formatting and regulatory filing into EDGAR, SEDAR, FSA and other systems.

Communications professionals turn to Business Wire to optimize and issue press releases, photos and multimedia to news organizations, journalists, trade publications, search engines, and individuals, with full-text posting to web sites, online services and databases. A range of distribution options enables members to target by geography, industry, news theme and audience demographics.

Founded in 1961, Business Wire has dual headquarters in San Francisco and New York, with 30 bureaus in cities including Los Angeles, Chicago, Boston, Miami, Paris, Frankfurt, London, Brussels, Tokyo, Toronto and Sydney and reciprocal offices throughout the world. Business Wire's patented NX data platform supports XML, XHTML and XBRL code that enhances news release interactivity, social media sharing and search engine optimization. More information about Business Wire and its services is located on its website at www.BusinessWire.com.

Business Wire
Global Event Services
310-820-9473
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(Source: Business Wire )


China Bio Energy Reports Fourth Quarter and Record 2008 Financial Results

HERCULES, CA and BILLERICA, MA, Mar 23, 2009 (MARKET WIRE via COMTEX) ----Bio-Rad Laboratories, Inc. (NYSE: BIO64.93, 0, 0%) and (NYSE: BIOb), a multinational manufacturer and distributor of life science research and clinical diagnostic products, and Bruker Corporation (NASDAQ: BRKR), a leading manufacturer of mass spectrometry (MS26.039, n.a., n.a.%) instruments, today announced that they have signed an exclusive partnership agreement to develop and market new products based on Bio-Rad's surface-enhanced laser desorption/ionization (SELDIundefined, undefined, undefined%) technology in combination with Bruker's matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF/TOF) mass spectrometers for applications of high-throughput protein profiling and identification. The products will provide new solutions for biomarker discovery, in particular, the detection and high-confidence identification of intact peptides and proteins under 30 kilodaltons, which are known to be challenging for currently available technologies to identify.

"We're confident that Bio-Rad's SELDI technology combined with the flexibility delivered by Bruker's TOF/TOF systems will offer tangible benefits to researchers for protein biomarker discovery," said Brad Crutchfield, Bio-Rad Vice President and Life Science Group Manager. "We welcome the opportunity to work with Bruker, a company that, similar to Bio-Rad, has a long history of advancing life science research through its commitment to customer support."

"We are excited about working with Bio-Rad," said Dr. Gary Kruppa, Vice President for Business Development at Bruker Daltonics. "Bruker Daltonics' high-performance TOF/TOF technology will bring a new dimension to protein profiling and identification, expanding the capabilities of Bio-Rad's established SELDI technology. New products based on this combination of technologies will allow access to new technical capabilities and new market segments in applied proteomics, enabling researchers to better identify and characterize new biomarkers."

About Bio-Rad

Bio-Rad Laboratories, Inc. (NYSE: BIO64.93, 0, 0%) and (NYSE: BIOb), has remained at the center of scientific discovery for more than 50 years, manufacturing and distributing a broad range of products for the life science research and clinical diagnostic markets. Bio-Rad is renowned worldwide among hospitals, universities, major research institutions, as well as biotechnology and pharmaceutical companies for its commitment to quality and customer service. Founded in 1952, Bio-Rad is headquartered in Hercules, California, and serves more than 85,000 research and industry customers worldwide through its global network of operations. The company employs over 6,500 people globally and had revenues exceeding $1.7 billion in 2008. For more information, visit www.bio-rad.com.

About Bruker Daltonics

Bruker Daltonics is a leading manufacturer of mass spectrometry (MS26.039, n.a., n.a.%) instruments and accessories for life science, pharmaceutical, biochemical and chemical research as well as for applied analytical tasks in forensics and food safety. Technical solutions are based on a comprehensive range of MALDI-TOF/TOF, ESI-Qq-TOF, ESI-ITMS, and ESI/MALDI-FTMS mass spectrometry systems, as well as automated sample handling systems and productivity enhancing software. For more information about Bruker Daltonics and Bruker Corporation (NASDAQ: BRKR), please visit www.bdal.com and www.bruker.com.

This release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements generally can be identified by the use of forward-looking terminology such as, "believe," "expect," "may," "will," "intend," "estimate," "continue," or similar expressions or the negative of those terms or expressions. Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements. For further information regarding the Company's risks and uncertainties, please refer to the "Risk Factors" in the Company's public reports filed with the Securities and Exchange Commission, including the Company's most recent Annual Report on Form 10-K, Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. The Company cautions you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof. Bio-Rad Laboratories, Inc., disclaims any obligation to update these forward-looking statements.

    For more information, contact:    Bio-Rad Laboratories, Inc.    Tina Cuccia    Corporate Communications Manager    510-724-7000    Email Contact        Bruker Corporation    Stacey Desrochers    Investor Relations    978-663-3660 x 1115    Email Contact            

SOURCE: Bio-Rad Laboratories

 http://www2.marketwire.com/mw/emailprcntct?id=876CC5C8A5A3B1D5    http://www2.marketwire.com/mw/emailprcntct?id=B10855C35E52DEC6    
 Copyright 2009  Market Wire, All rights reserved.
 
 

Bio Medica sales down, net loss up in 4Q

American Bio Medica Corp. reported lower sales, and a bigger net loss, for the fourth quarter.

The Kinderhook, N.Y. company, which makes drug-testing kits, had a net loss of $672,000, or 3 cents a share, for the three months ended Dec. 31. This compares to a net loss of $28,000, or less than a penny a share, a year earlier.

Sales for the quarter totaled $2.3 million, down from $3.3 million in the year-ago period.

"Sales in the fourth quarter of 2008 suffered greatly, especially in December of 2008, as a result of the overall condition of the global economy," said Stan Cipkowski, CEO of American Bio Medica. "More specifically, sales in our national account division, which sells primarily to the workplace market and historically sees year over year growth, declined as new and existing employment levels continued to be negatively impacted. In addition, budget cuts and price pressure continue to negatively affect our government sales division. On a brighter note, we have continued to see growth in sales outside of the United States, especially in Latin America."

For all of 2008, American Bio Medica (Nasdaq: ABMC) reported a net loss of $850,000, or 4 cents a share, on sales of $12.6 million. This compares to a loss of $990,000, or 5 cents a share, in 2007.


Cynvec to Present at the BIO National Venture Conference

NEW YORK, March 25, 2009 /PRNewswire via COMTEX/ ----Cynvec LLC, a privately held biotechnology company focused on developing novel cancer therapies that harness the apoptotic ability of the sindbis viral vector, today announced that Frank Stonebanks, President and Chief Executive Officer, will present at the BIO National Venture Conference in Boston on Wednesday, April 1, 2009 at 1:45 p.m. ET.

About Cynvec LLC

Cynvec, a privately held biotechnology company, is developing proprietary cancer therapies based on the apoptotic sindbis oncolytic viral vector, a novel technology that targets the over expressed laminin receptor on the surface of many solid tumors without affecting normal cells. Under an exclusive worldwide license from the NYU School of Medicine, Cynvec is developing its lead product, CYN 101, to be used as a single agent or in combination with cytotoxics, monoclonal antibodies, chemotherapeutic agents and radiation. CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly significant survival rates in pre-clinical models of ovarian and pancreatic cancer as both a single agent and in combination with licensed chemotherapies. Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real time cancer diagnostic. Cynvec expects to begin Phase I clinical trials of CYN 101 in ovarian cancer in the third quarter of 2009. The sindbis vector has also demonstrated in vivo efficacy delivering a variety of cytokines directly to tumor sites. Additionally, a screening program is underway to identify small molecules that bind to the laminin receptor, which is implicated in Alzheimer's disease, multiple sclerosis and Parkinson's. Further information on Cynvec can be found at www.cynvec.com.

SOURCE Cynvec LLC

 
 http://www.cynvec.com    
 Copyright (C: 2.909, n.a., n.a.%) 2009 PR Newswire. All rights reserved


BIO Holds Diversity Summit at 2009 BIO International Convention in Atlanta

WASHINGTON, Mar 25, 2009 (BUSINESS WIRE) ----The Biotechnology Industry Organization (BIO64.93, 0, 0%) invites leaders in workforce development, science education, health disparities and community outreach to attend Fulfilling the Promise: Diversity in Biotechnology Summit on Monday, May 18, 2009 from 8:30 a.m. - 5:00 p.m. at the Omni Hotel at CNN Center in Atlanta. Part of the 2009 BIO International Convention, the inaugural event will include discussions with industry representatives, policymakers and community leaders.

"Diversity is important to our industry and this summit will focus on how to encourage more diversity within the workforce," said Robbi Lycett, vice president of Conventions & Conferences at BIO. "We are pleased to bring together individuals from industry, academia, government and the non-profit sector to discuss important topics related to diversity within biotechnology, such as economic and workforce development, health disparities and community outreach, education and access."

Highlights include:

-- Plenary breakfast featuring Atlanta Mayor Shirley Franklin and Georgia Representative John Lewis;

-- Economic/workforce development panel featuring Dr. Michael L. Penn, Jr., Genentech;

-- Legislative roundtable discussing federal and state legislative initiatives moderated by US Delegate Donna Christensen;

-- Health disparities and community outreach panel featuring Dr. Carolyn Britton of the National Medical Association;

-- A town hall meeting on education, access and awareness of the future of technology with Dr. Otis Brawley of the American Cancer Society and Dr. Eve Higginbotham from the Morehouse School of Medicine;

-- As well as keynote addresses from Governor Luis G. Fortuno of Puerto Rico and the Honorable Louis Sullivan.

For additional information or to register for the Diversity in Biotechnology Summit, please contact Julia Moorhead at jmoorhead@bio.org or at 202.962.9509 by Friday, April 17, 2009.

To register for the 2009 BIO International Convention, please visit http://convention.bio.org.

The BIO International Convention helps to support BIO programs and initiatives. BIO works throughout the year to create a policy environment that enables the industry to continue to fulfill its vision of bettering the world through biotechnology innovation. For more information on the global event for biotechnology, including program and housing information, please visit http://convention.bio.org.

About BIO

BIO represents more than 1,200 biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. BIO also produces the BIO International Convention, the world's largest gathering of the biotechnology industry, along with industry-leading investor and partnering meetings held around the world.

Upcoming BIO Events

BIO IP Counsels' Committee Conference March 25-27, 2009 Phoenix, AZ

BIO National Venture Conference March 31-April 1, 2009 Boston, MA

BIO Windhover 2009 April 13-15, 2009 New York, NY

BIO-LES Business Development Basics Course May 15-17, 2009 Atlanta, GA

BIO-LES Advanced Business Development Course May 15-17, 2009 Atlanta, GA

BIO Executive Presentation Workshop May 17, 2009 Atlanta, GA

BIO Human Resources Conference May 17-19, 2009 Atlanta, GA

2009 BIO International Convention May 18-21, 2009 Atlanta, GA

BioEquity Europe June 9-10, 2009 Munich, Germany

World Congress on Industrial Biotechnology & Bioprocessing July 19-22, 2009 Montreal, Quebec, Canada

SOURCE: Biotechnology Industry Organization (BIO64.93, 0, 0%)

    Biotechnology Industry Organization (BIO: 64.93, 0, 0%)     Tracy Krughoff, 202-312-9274     tkrughoff@bio.org    
 Copyright Business Wire 2009
 

Monday 23 March 2009

New & Relaxing Health & Beauty Treatments at Luxury Hotels In England

Many of us remember seeing Dawn French immerse her head under a chocolate fountain during an episode TV's The Vicar of Dibley, but leisure club guests at Barceló Shrigley Hall Hotel, Golf & Country Club in Cheshire can enjoy a more beneficial and professional chocolate experience as part of a choice of new beauty treatments at the Shrigley Hall hotel.

Donna Hartley MBE, Shrigley Hall's health & leisure club manager, explains the advantages of chocolate therapy skin treatment:

"Chocolate Therapy for the face is the ultimate indulgent facial that not only smells great, it also benefits your skin too. Using 100% Cocoa and Natural Cocoa Butter, skin is nourished, oxygenated and hydrated with natural anti-oxidants and minerals. Skin is left looking luminous and the smell releases endorphins for a feeling of wellbeing from within," she says.

The treatment is also available as a relaxing body therapy using Dead Sea Salts, Essential Oils and warm 100% Pure Cocoa Butter.

In addition to the Chocolate Therapy, Barceló Shrigley Hall Leisure Club is also introducing a special bamboo massage treatment that uses bamboo poles.

"The aim of bamboo massage is to strengthen muscles, reactivate circulation and relive stress," says Donna. "Unlike any massage that you have experienced before, the technique uses silky bamboo canes to create particular rolling and unique massage movements, which create a deep feeling of relaxation.

"The massage also targets specific reflexology points and uses bamboo bio extract to make skin feel nourished and restored," continues Donna.

Another therapy likely to prove popular is Green Tea Abdomen Treatment.

"Green Tea Abdomen Treatment has proved immensely successful. It is a non-invasive colonic treatment with a dual action that treats both the internal digestive system and also firms the skin, relieving tension and bloating," says Donna.

"A natural peel-off mask, which is also part of the treatment, contains Green Tea, Seaweed and Alginate and has an extraordinary capacity to reduce excess liquids. Combined with a unique massage, it's an ideal treatment to enjoy prior to a major event, holiday or for those suffering with common abdominal problems."

More information about membership at Shrigley Hall's leisure club and spa & beauty offers can be obtained by calling the hotel on 01625 575 757 or emailing
shrigleyhall@barcelo-hotels.co.uk.

Reserving beauty treatments at 11 Barceló Hotels, including Barceló Shrigley Hall, is now easier than ever, as bookings can now be made on line at
www.barcelo-hotels.co.uk. Treatments include pedicures and manicures, as well as back, neck and facial massages.

Links:

http://www.barcelo-hotels.co.uk/hotels/northern-england/barcelo-shrigley-hall-hotel-cheshire/beauty/ 

http://www.barcelo-hotels.co.uk/hotels/northern-england/barcelo-shrigley-hall-hotel-cheshire/health-leisure/ 

http://www.barcelo-hotels.co.uk/health-and-beauty/treatments 

http://www.barcelo-hotels.co.uk/health-and-beauty/offers 

http://www.barcelo-hotels.co.uk/hotels/northern-england/barcelo-shrigley-hall-hotel-cheshire/offers/



Beauty-Feud History, How ‘Angels’ Hide Cellulite, and Red Lips Are In

Skin
• Victoria's Secret Angel Marisa Miller hides cellulite with self-tanner. Maybe Lindsay is onto something? [Fox News]

Makeup
• Elizabeth Arden and Helena Rubenstein may have founded their companies at the same time and lived in the same hood, but they never met. The fierce business rivalry is explored tonight in The Powder & the Glory, airing on PBS. (Check local listings for airtime.) Beauty catfight! [WSJ]

• Red lips are in! Are they ever not? See how to wear them. [Beauty Reporter/Allure]

• Clarins is revamping its U.S. image in hopes of making it sexier and reaching the Hispanic market. We can't remember the last time we bought Clarins, so this is probably wise. [WSJ]

Hair
• Does anyone know why Fergie's scalp is … orange? This blogger can't figure it out. Glaze? Radioactive makeup? [Beauty Department/Glamour]

Nails
• Revlon is releasing a line of polishes that smell addictively fruity. This really won't help nail biters one bit. [Fashionista]

Plastic Surgery
• Icky blind item: An unnamed fashion editor apparently had too much fat pumped into her lips, earning her the name, "Hamster." We don't know what's worse: That this happened or that it's a blind item. [NYP]



Wednesday 11 March 2009

Barbie has perpetuated an unattainable standard of beauty for 50 years

Barbie has perpetuated an unattainable standard of beauty for 50 years

Barbie revolutionized the toy industry. You can give her props for that. And you can't fault a woman for looking so good 50 years later. Getting this far with no sagging, bulging or graying is a monumental achievement, and she deserves a trophy. But forgive me if I'm not in the mood to celebrate.

The problem is Barbie helped perpetuate a standard of beauty that's almost impossible for a woman to attain. Even Stacey Handler, the granddaughter of the doll's creator, has had to deal with the constant pressure. In a 2000 article, she described her struggle with being overweight and trying to live up to her grandmother's standard. "Barbie has been like a flawless sister," she said. She "has this perfect image and there were times when I felt that I was in the shadow of the ideal."

And what of little girls all over America who are constantly bombarded with Hollywood and magazine images that say they're less than beautiful the way they are? Do you think it's a coincidence plastic surgeries have soared and eating disorders have increased? It's not all Barbie's fault, or course. But she has helped fuel the beauty industry.

Such a standard can be particularly damaging to children from non-European ethnic backgrounds whose features differ from the Western mainstream. Black girls are particularly vulnerable because not only can body image be affected, but also their feelings about hair and facial features.

My two daughters, thank God, told me recently they don't like Barbie anyway because the only thing they can do with her is dress her up. They prefer American Girl dolls that are 18 inches tall, closer to real life, come with an interesting historical story and, according to one of my daughters, are "flat-chested" and don't make little girls feel they have to have big boobs to be beautiful. (She said it, not me.) My girls also like the company's Just Like You dolls that they can dress to wear what they're wearing.

So Happy Birthday, Barbie, but don't send us an invitation to the party. We're too busy learning to love who we are. 

With her tiny figure and controversial accessories, do you think Barbie is a poor role model for girls? Should parents stop buying the doll? Sound off! 



PEEP SHOW Star Mel B Models Ultimo's Sexy Styles

Tickets are available now, including specially priced tickets during preview performances, for a glimpse of the all-new, modern striptease revue. Set in a new, custom-designed theater, PEEPSHOW will highlight the art of the tease featuring an all-female powerhouse band and more than 20 sexy dancers from film, TV, Broadway and beyond for a show unlike any other on The Strip.

PEEPSHOW will open for preview performances on March 30, 2009, with an opening night gala planned for April 18, 2009. Tickets range from $65 - $100 + tax, with a VIP package available at $165 + tax per person. The VIP package includes premium seating at one of the PEEPSHOW cabaret tables and includes tableside bottle service.

From March 30 - April 17, 2009 preview performance ticket prices range from $59 - $91 + tax with the VIP package available at $149 + tax per person.

PEEPSHOW is a story of sexuality and empowerment told through dance and contemporary popular music, featuring the "Peep Diva," a bold and powerful woman with all the answers, who guides the timid "Bo Peep," a modern woman who has yet to find her own power and sexuality, on a swift journey of awakening and self-discovery during which she's inspired through sensual awareness and blossoms into a sexy, daring, provocative and more confident woman.

PEEPSHOW will perform Sunday, Monday, Tuesday and Friday at 8 p.m. and Thursday and Saturday at 7 p.m. and 9:30 p.m. with no show on Wednesday. Tickets are available by calling The Planet Hollywood Box Office at 702-785-5000 or 877-333-9474, Ticketmaster at 800-745-3000 or online at Ticketmaster.com.

For groups of 10 or more, please call 702-785-5394 / 866-633-0195 or Groups@BASEentertainment.com.

For more information please visit www.LasVegasPeepshow.com.

Photos courtesy of Ultimo.co.uk.


Mel B


Mel B


Mel B


Mel B

PEEP SHOW Star Mel B Models Ultimo's Sexy Styles


Former Spice Girl and RENT star Mel B is set to make her debut on the Las Vegas stage later this month as Peep Diva in Jerry Mitchell's burlesque extravaganza Peep Show. 

Ultimo Lingerie founder Michelle Mone created a sexy Burlesque theme for the Ultimo Spring 2009 photo shoot starring spokesmodel Mel B, all of which fit in perfectly to her upcoming stint in Peep Show. The photos were taken at The Pigalle Club, a famous supper and burlesque club in central London, which provided the perfect inspiration.

Rehearsals are underway for The Strip's hottest and most anticipated new show, PEEPSHOW, at Planet Hollywood Resort & Casino. Starring TV personality and chart-topping musical artist Mel B, a member of the world sensation Spice Girls, and General Hospital star and Dancing With the Stars first season champion Kelly Monaco, PEEPSHOW is a highly stylized, full-throttle production show that combines sexy striptease and celebrity with high-level production values and a dash of passion.

Tickets are available now, including specially priced tickets during preview performances, for a glimpse of the all-new, modern striptease revue. Set in a new, custom-designed theater, PEEPSHOW will highlight the art of the tease featuring an all-female powerhouse band and more than 20 sexy dancers from film, TV, Broadway and beyond for a show unlike any other on The Strip.

PEEPSHOW will open for preview performances on March 30, 2009, with an opening night gala planned for April 18, 2009. Tickets range from $65 - $100 + tax, with a VIP package available at $165 + tax per person. The VIP package includes premium seating at one of the PEEPSHOW cabaret tables and includes tableside bottle service.

From March 30 - April 17, 2009 preview performance ticket prices range from $59 - $91 + tax with the VIP package available at $149 + tax per person.

The Shady Nook Cafe - The Middle of America

The Shady Nook Cafe - The Middle of America
The Shady Nook Cafe was located inside the Shady Nook Truck Stop, just west of Kearney, Nebraska near the 1733 Ranch and the 1733 mile marker for the Lincoln Highway. The middle of America was first located at the half-way point between Boston and San Francisco along the Lincoln Highway - the first trans-American highway. The Shady Nook Cafe was 1733 miles from Boston and 1733 miles from San Francisco. Most political pundits aspire to pander their comments to the extremes of the various political parties, thinking the left-wingers and the right-wingers held the keys to nominations, and thus the political power base. However, this thinking has left America damaged from the division and political rhetoric of the extremists, while Middle America has been ignored and excluded from debates over political issues and governmental policy. Candidates who obtain their party's nominations pander to those extremes, only to suffer from whiplash in trying to then court the Middle of America - which really determines the winner of each Presidential election. This blog will attempt to address political topics from the rational middle, where common sense, rational thought, and concerns about "doing the right thing" for the "best interest of the country" dominate over pandering to special interests, Euro-centric liberalism, the religious extremes, or the liberal dominated mass media. Come in to the Shady Nook Cafe, get a cup of coffee, and let's chat about America - from the Middle.




'American Idol' sex-line snafu: And you thought Bikini Girl was racy!

'American Idol' sex-line snafu: And you thought Bikini Girl was racy!

Mar 10, 2009, 06:52 PM | by Kate Ward

Categories: 'American Idol 2009'

Americanidolkatrina_lThink American Idol is a family-friendly program? Think again. Yesterday -- less than one week after Cowell & Co., crowned a top 13 for the first time in Idol history -- the show's producers scrambled to find a new call-in number after discovering that 1-866-IDOLS-13, the intended number for the 13th contestant, was actually...(wait for it) a sex line. Sure, this would be perfect if Bikini Girl (real name: Katrina Darrell, pictured) was still in the competition, but will the special, one-time-only, inconsistent number bode well for the contestant awarded the coveted pimp spot? Or will dialing confusion hurt their chances (if we see Danny, Adam or Lil in any other slot tonight, I think we can assume that the producers are worried about the latter)? Either way, you've got to give it up to a phone sex company with the brains to choose a number that takes advantage of clumsy Idol fans, no?

Monday 9 March 2009

Sylvie Guillem on swapping ballet for contemporary dance

From 
February 23, 2009

Sylvie Guillem on swapping ballet for contemporary dance

Sylvie Guillem has moved into producing and starring in her own projects - and she doesn't miss classical dance one bit

Sylvie Guillem

Sylvie Guillem is unbelievably elegant but she hasn't made the slightest effort. Her face is scrubbed free of make-up, her long auburn hair is tied back with casual aplomb, and she's dressed like a truck driver. Scruffy and natural - is this how ballerinas are supposed to look? Yet there has always been something extraordinary about this glamorous French artist, and no matter how much she downplays it, her innate charisma can't help but assert itself.

She may not think so, but Guillem is the nearest thing dance has to a Hollywood star, the one dancer whose phone calls are sure to be answered. These days she also wields the power of an LA producer, organising and starring in her own projects, collaborating with the most innovative talents around. For her latest, Eonnagata, she will be directed by Robert Lepage and dressed by Alexander McQueen - and you can't get more A-list than that. Guillem may have danced her last Juliet three years ago, but her career is even more remarkable now than it was in the days when she reigned over the Royal Ballet.

Unlike Darcey Bussell, her long-standing rival at Covent Garden, Guillem is famous only for what she does on stage, not for what she does off. Where Bussell posed for fashion shoots, sold her story to gossip magazines and danced on the telly with French and Saunders, acting as a kind of ambassador for dance in the wider world, Guillem spent her free time working with avant-garde choreographers and pursuing intellectual growth (she is French, after all). Celebrity, it would seem, wasn't part of the plan.

"I would feel embarrassed to be famous," she says now. "I don't like to be flattered all the time, I don't like to be fawned over. I don't take pride in being recognised in the street. It's not my goal. My goal is to be appreciated for what I do. I am proud of what I give on stage but I wouldn't be proud of making a silly appearance at a party, or being in silly pictures in a magazine, or of having a scandal in my sex life and being recognised for that. It's so banal."

And as for fashion shoots, forget it. "I get asked all the time and I don't do them. I'm not a model, why should I do fashion shoots? Models do it so much better and if you dress me that way I won't look like myself." Typical, then, that when French Vogue asked her to take part in a photo shoot seven years ago she insisted on doing it in the nude.

Her body has always been her USP, amazing even by ballet's high standards, and its sheer physical superiority has changed the way British audiences view dance. Tall and ultra-thin ("I look like an asparagus"), she is hyperflexible, with flamboyant long legs that when lifted can extend above her ears. But there is also a visceral sensuality to her movement, a sophisticated refinement and a steely strength that has protected her from recurrent injury. It's the product of fabulous genes and years of rigorous training, first as a gymnast and later as a dancer. "I was lucky, I never really had a lot of trouble with my shape."

Even now, in her forties, her body, relaxing on a prosaic sofa in her modest Sadler's Wells dressing room, looks as if it can do anything. "I don't feel older," she claims. "When you are young you don't think of the body. Now I do, that's the difference. A few things are harder, but in the end you find more intelligent ways of moving because you think more about what you are doing. But of course when you dance you are in pain and each time I have a pain I remember that I had the same pain when I was 20 - I was at the osteopath every three days. You just don't notice it when you are young.